South San Francisco Clinic — South San Francisco, CA
South San Francisco Clinic is a community health center clinic at 306 Spruce Ave, South San Francisco, CA 94080, open 40 hours a week. That matches the 40-hour week of a typical California clinic. It is run by San Mateo County Health Services Agency, which serves 4,975 patients across 13 clinic locations.
- Address: 306 Spruce Ave, South San Francisco, CA 94080 · Directions
- Phone: (650) 877-7070
- Website: www.co.sanmateo.ca.us
- Weekly hours: 40 (California clinic median: 40)
- Operated by: San Mateo County Health Services Agency (federally qualified health center)
- Care offered by this health center: primary care, dental care, mental health care, substance use treatment, eye exams, children’s checkups, women’s health, and telehealth
Care and screenings at San Mateo County Health Services Agency
Patients came to San Mateo County Health Services Agency for these services in 2025. The numbers cover the whole health center, not only this clinic.
| Service | Patients | What it counts |
|---|---|---|
| Dental care | 1,054 | patients had dental exams |
| Mental health care | 1,299 | patients treated for depression or anxiety |
| Substance use treatment | 94 | patients in treatment |
| Eye exams | 422 | patients had eye exams |
| Well-child visits | 251 | children had checkups |
| Flu shots | 836 | patients vaccinated |
| Cervical cancer screening | 113 | patients tested |
| Breast cancer screening | 356 | patients screened |
| Family planning | 304 | patients served |
| Diabetes care | 471 | patients with diabetes |
| Blood pressure care | 622 | patients with hypertension |
| Asthma care | 147 | patients with asthma |
| HIV testing | 630 | patients tested |
| Hepatitis C testing | 534 | patients tested |
| Childhood lead tests | 64 | children tested |
San Mateo County Health Services Agency also provides care by telehealth.
Who San Mateo County Health Services Agency serves
4,975 patients used San Mateo County Health Services Agency in 2025. 95% live at or below the poverty line and 98% are at or below twice the poverty line. 3,839 patients were experiencing homelessness and 36 were veterans.
| Measure | This center | CA median | U.S. median | vs CA |
|---|---|---|---|---|
| Patients at or below the poverty line | 95% | 75% | 65% | +20 pts |
| Patients at or below 200% of the poverty line | 98% | 95% | 92% | +3 pts |
| Measure | This center | CA median | U.S. median | vs CA |
|---|---|---|---|---|
| Uninsured patients | 21% | 8% | 14% | +14 pts |
| Medicaid or CHIP patients | 65% | 71% | 42% | −6 pts |
| Medicare patients | 11% | 8% | 11% | +3 pts |
| Privately insured patients | 2% | 10% | 24% | −8 pts |
Quality of care at San Mateo County Health Services Agency
San Mateo County Health Services Agency is at or above the California median on 2 of 7 preventive-care measures. Higher is better on every line.
| Measure | This center | CA median | U.S. median | vs CA |
|---|---|---|---|---|
| Adults with high blood pressure under control | 67% | 68% | 68% | −1 pts |
| Women 52–74 screened for breast cancer | 62% | 59% | 54% | +2 pts |
| Women 24–64 screened for cervical cancer | 35% | 60% | 54% | −24 pts |
| Adults 46–75 screened for colorectal cancer | 46% | 44% | 44% | +2 pts |
| Patients 12+ screened for depression | 38% | 68% | 77% | −30 pts |
| Adults assessed for tobacco use | 79% | 86% | 86% | −7 pts |
| High-risk adults on statin therapy | 74% | 79% | 79% | −5 pts |
Staffing at San Mateo County Health Services Agency
The health center employs 39 full-time-equivalent staff, including 7 physicians, nurse practitioners, physician assistants and midwives, 2 dental staff and 5 mental health staff. That is 711 patients per clinical provider against the California median of 869 and the U.S. median of 930. Patients made 37,297 visits, about 7.5 per patient.
Patients from ZIP 94080
363 San Mateo County Health Services Agency patients live in ZIP 94080, and 25% of them are uninsured. Other health centers also serve this ZIP:
- North East Medical Services — 2,647 patients from 94080
- Mission Area Health Associates DBA Mission Neighborhood Health Center — 121 patients from 94080
- South County Community Health Center, Inc. — 90 patients from 94080
- Healthright 360 — 46 patients from 94080
Community health centers near South San Francisco Clinic
North East Medical Services - 200 Linden
North East Medical Services - Sullivan Suite 150
Hawkins Village Medical Clinic
North East Medical Services - Leland
North East Medical Services - Eastmoor
More San Mateo County Health Services Agency locations
Daly City Youth Health Center
Daly City Youth Health Center
Central County Mental Health Ctr
Coastside Health Center
See all 13 San Mateo County Health Services Agency locations
More community health centers in South San Francisco and across California.